The IL12RB2 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to IL-12 R beta 2, and IL12RB2. This antibody recognizes Human, Mouse, and Rat antigen. The IL12RB2 Polyclonal Antibody has been validated for the following applications: ELISA, and Immunohistochemistry.
Description
The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation